Scientists Think They've Unlocked The Secret of Long-Term Lyme Disease Symptoms

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Scientists Think They've Unlocked The Secret of Long-Term Lyme Disease Symptoms
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Scientists may have discovered a new way of tackling the lingering, debilitating effects of Lyme disease, the tick-borne illness that can lead to flu-like symptoms and a rash called erythema migrans.

Patients with PTLDS usually get better eventually, but it can take a long time for people to feel fully well again. There's currently no proven treatment for the condition, as there is for Lyme disease itself.on nervous system tissue extracted from euthanized rhesus macaque monkeys, observing the effects on both the frontal cortex in the brain and the dorsal root ganglion in the spinal column.B.

than in samples exposed to live bacteria. What's more, the dead bacteria also caused cell death in brain neurons.was particularly evident in the frontal cortex, which helps coordinate movement, organize thoughts, and control working memory. This might be where PTLDS fully or partly originates, the researchers suggest.

"As neuroinflammation is the basis of many neurological disorders, lingering inflammation in the brain due to these unresolved fragments could cause long-term health consequences,"Brain scans of patients with PTLDS do indeed show persistent inflammation in the brain, but as yet, the cause of this neuroinflammation hasn't been identified. This latest study looks to be an important step forward in finding that cause.finds its way into the brain in the first place.

"Persistence of symptoms in some patients post-treatment indicates that in a subset of these patients,

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