Scientists said Saturday they had identified the mechanism through which air pollution triggers lung cancer in non-smokers, a discovery one expert hailed as 'an important step for science – and for society'.
in non-smokers, a discovery one expert hailed as"an important step for science – and for society".
Air pollution has long been thought to be linked to a higher risk of lung cancer in people who have never smoked. But there was an"inconvenient truth" with this model, Swanton said: Previous research has shown that the DNA mutations can be present without causing cancer – and that most environmental carcinogens do not cause the mutations.The research team from the Francis Crick Institute and University College London analyzed the health data of more than 460,000 people in England, South Korea, and Taiwan.
Finally, they analyzed nearly 250 samples of human lung tissue never exposed to carcinogens from smoking or heavy pollution. Swanton said he hoped the finding would"provide fruitful grounds for a future of what might be molecular cancer prevention, where we can offer people a pill, perhaps every day, to reduce the risk of cancer".Suzette Delaloge, who heads the cancer prevention program at France's Gustave Roussy institute, said the research was"quite revolutionary, because we had practically no prior demonstration of this alternative way of cancer forming.
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