A new biomaterial mimicking youthful tissue reprograms aged heart cells—without touching the cells themselves.
Scientists may have found a way to rewind the heart’s biological clock without even touching the cells.A team of researchers led by Assistant Professor Jennifer Young from the Department of Biomedical Engineering at the National University of Singapore has developed a new lab-grown material that shows promise in slowing, and even reversing, some effects of ageing in the heart.
Notably, this rejuvenation occurred even when the underlying material remained stiff.Further analysis revealed widespread changes in gene expression, involving thousands of genes associated with ageing and cellular function.
Cell Rejuvenation DECIPHER ECM Extracellular Matrix Gene Expression Heart Ageing Lab-Grown Biomaterial Regenerative Therapy Tissue Stiffness
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