Yale scientists restored circulation to pigs' hearts and brains one hour after they died, according to new research.
Scientists at the Yale School of Medicine restored circulation to pigs’ hearts and brains one hour after they died, according to new research published Wednesday in the journalthat raises new questions about the future of life-support measures—though researchers say the technology is still “very far” from human use....
Even though the pigs did not fully regain consciousness, the procedure decreased cell death, preserved tissue integrity and restored molecular and cellular processes in vital organs, including the heart, liver and kidney, the research found. OrganEx, which also includes a pulse generator and heater, is a full-body version of a previously studied technology called BrainEx, which was used in 2019 research.
In the research, OrganEx outperformed an alternative approach called extracorporeal membrane oxygenation , which is currently used in clinical settings to provide life support to hospital patients by pumping blood to a machine that removes carbon dioxide and refills the body with oxygen-rich blood. Yale University Senior Research Scholar Stephen Latham said in a press conference that the technology is “very far away from use in humans,” primarily because it still does not restore function to all organs.The research works off a similar 2019 Yale study that used BrainEx to restore brain activity in dead pigs. Researchers called the results from the new OrganEx study “stunning,” and a step “in the right direction.
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