The team were inspired by see-through sea creatures like squids.
Engineering at the University of California, Irvine, and colleagues genetically engineered human cells—which are relatively transparent—to expressreflectinA number of the cells took up the DNA, and used the genetic coding from the squid DNA to makeproteins were found to group together in small clusters. When the scientists exposed the cells to salt, theproteins grouped together even tighter, creating structures big enough to reflect light.
The ability to make mammalian cells and tissues more transparent for imaging has proven invaluable for better understanding their organization in 3-D, said Gorodetsky."Our now-demonstrated ability to engineer and tune the transparency of living human cells could complement these existing exciting efforts."
However, Gorodetsky said:"Although this study opens up a lot of possibilities, a great deal of work will be necessary to extend our methods to other cell types and ultimately even tissues. One of the key issues is the incomplete understanding of the structure of our squid protein.", professor in electrical and computer engineering at the University of Illinois at
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