Scientists identify two newgenes involved in hemiplegic migraine qut
is a severe subtype of migraine, usually inherited dominantly in families, where people experience significant weakness or paralysis on one side of their body, along with other serious migraine symptoms," Professor Griffiths said.sequencing methods, we implicated two genes, CACNA1H and CACNA1I, which are ion channel genes involved in controlling calcium levels in the brain and potentially affecting neurotransmitter release..
Professor Griffiths said current evidence indicated that complex traits were likely to be underpinned by a combination of both common and rare variants. "These genes can modify HM disease risk, which supports the hypothesis that the disease may have complex heritability, in addition to the strictly single gene forms.
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