Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the understanding of early neural development -- which is fundamental for the further understanding of neurodevelopmental syndromes.
Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the understanding of early neural development -- which is fundamental for the further understanding of neurodevelopmental syndromes.
Although every cell in our body carries the same genetic information, not every cell is identical. Cells get direction on what type of cell to become: muscle cells, blood cells, neurons, etc. In the early stages of biological development, stem cells transition from a state of"pluripotency," which is the ability of an unspecialized cell to develop into any number of mature, specialized cell types based on the biological signals and inputs they receive along the way.
Gardini and his team assessed the Integrator subunit INST10, which, across cells from both the central and peripheral nervous systems, was more abundant than other subunits of the same Integrator protein complex; this confirmed that neural cells had some essential need for INST10.
Improved understanding of a neural pathway connecting light-sensitive cells in the retina with the cortical brain regions involved in mood and cognition has implications for the development of ...
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