A new study has discovered how a lipid molecule found at high levels within tumors undermines the anti-cancer immune response and compromises a recently approved immunotherapy known as adoptive cell therapy (ACT) using tumor infiltrating lymphocytes, or TIL-ACT.
Scientists identify and show how to target a key tumor defense against immune attack." ScienceDaily. ScienceDaily, 24 April 2024. <www.sciencedaily.comLudwig Institute for Cancer Research. . Scientists identify and show how to target a key tumor defense against immune attack.Ludwig Institute for Cancer Research."Scientists identify and show how to target a key tumor defense against immune attack." ScienceDaily. www.sciencedaily.
The MYCN oncoprotein plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma, the tumors become ... A patient's own immune cells, multiplied into an army of billions of immune cells in a lab, can be used as a living medicine against metastatic melanoma, an aggressive form of skin cancer, as the TIL ...
A new approach to cancer immunotherapy that uses one type of immune cell to kill another -- rather than directly attacking the cancer -- provokes a robust anti-tumor immune response that shrinks ... Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T ...LIVING & WELL
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