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Although the underlying pathology is similar in most with the condition, the rates and severity of their deterioration varies.The researchers started with a group of 500 Alzheimer's patients, following them over the course of two years. The drop-out rate was relatively high however, with only 169 patients still involved with the study by the end of that two-year period.were significant for all of the participants, though there was sufficient variation to uncover some relationships.
And it's not just the patients who are affected. Unsurprisingly, the burden on caregivers rose as cognitive abilities declined, suggesting those who support patients in their daily lives need to be considered in weighing up treatment options and disease progression, the researchers say., the findings are robust enough to suggest that demographics, medical history, and measures of daily activity could be enough to predict the rate of cognitive decline brought on by Alzheimer's.
"These findings underscore the importance of a comprehensive treatment approach, considering both patient and caregiver variables, in the diagnosis and treatment of early-stage Alzheimer's disease,"
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