Scientists hail the development as a significant breakthrough that could make a huge difference in the war against bird flu
H5N1 cannot currently pass between people and there have only been eight cases in humans since December 2021, all from direct contact with poultry after UK scientists successfully gene edited a group of birds to fully withstand the virus with no notable side effects.has been shown to reduce the risk of a flu infection, with chickens given complete resistance to avian flu when three of their genes were edited.
“Chickens that are genetically resistant to avian influenza could prevent future outbreaks. Our findings suggest gene editing as a possible route,” said Alewo Idoko-Akoh, of Edinburgh University. The genetically engineered chickens were created by gene editing “germ” cells of normal adult chickens – cells in the body that turn into sperm and eggs. The resulting offspring was then tested for resilience to bird flu.
“However, there are still many detailed considerations, some of them regulatory in some parts of the world that will need to be addressed before this work translates into clear applied benefit,” he added.– including chickens, ducks, turkeys, geese, pigeon, partridge, quail, guinea fowl and pheasants – were culled in the UK last year.
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