Scientists Have Created Cancer-Fighting E. Coli Bacteria

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Scientists Have Created Cancer-Fighting E. Coli Bacteria
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Genetically engineered E. coli strains killed a variety of different cancer types in mice.

In both lab and mice experiments, mp105 and m6001 appeared to work as expected. Mp105 was found to have direct and indirect effects on the mice’s cancers. It outright killed cancer cells, but it also depleted tumor-associated macrophages—a group of immune cells found in tumors that are thought to aid their survival—and it seemed to boost the body’s natural immune response to the cancer. M6001 had even more potent anticancer activity against the solid tumors it was deployed against.

Of course, this is just a single study involving mice. Much more research has to be done to validate the results seen here and to test out long-term safety before human trials would enter the picture. There might also still be ways to improve the effectiveness of the team’s bacteria. But if their research continues to show promise, the team believes that their two-pronged approach would be able to cover a variety of cancers. Mp105 could treat many different cancers systematically, for instance, while m6001 could help control solid tumors locally, including in combination with mp105.

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