Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development

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Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development
Human BiologyForensicsGene Therapy
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In a discovery that could redefine how we understand cellular resilience and adaptability, scientists have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development." ScienceDaily. ScienceDaily, 25 December 2024. <www.sciencedaily.comScripps Research Institute. . Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development.

Droplet systems such as DNA droplets, which are formed by liquid-liquid phase separation of macromolecules, play an essential role in cellular functions. Now, by combining the technologies of DNA ... Chemists have made a discovery that supports a surprising new view of how life originated on our planet. They demonstrated that a simple compound called diamidophosphate , which was plausibly ...

In a changing climate, understanding how organisms respond to stress conditions is increasingly important. New work could enable scientists to engineer the metabolism of organisms to be more ... Cellular processes such as transcription often take place in tiny cellular droplets called condensates. A new study shows the mechanism by which small molecules, including cancer drugs, are ...Brain Cells Remain Healthy After a Month on the International Space Station, but Mature Faster Than Brain Cells on Earth

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