“We now have the best 3D maps of the LRP2 protein ever created.'
Nephrologists and neuroscientists collaborated at Columbia University to develop 3D maps of proteins and how they aid the organs' ability to filter toxins.
Along with colleagues from other institutions, they revealed for the first time a picture of a protein that can make or break a person's life that is clear enough to explain how it functions: as a tiny ferry for molecules that must pass through nearly a trillion cell membranes in tissues and organs ranging from kidneys and brains to the inner ear and the lungs' alveoli, according to"With new mechanistic understanding of this key protein and how mutations in it can shut it down, we...
The new high-resolution protein structures could provide therapeutic leads for treating conditions as common as acute kidney injury, chronic kidney disease, and, as well as those that are uncommon, like Donnai-Barrow syndrome, a genetic disorder with a variety of physical and mental consequences. With the help of Dr. Beenken's arduously acquired LRP2 samples, co-corresponding author Dr. Anthony Fitzpatrick and Beenken gathered a large amount of structural data. The researchers then created 3D protein structures with nearly atomic detail, skillfully utilizing robust"We now have the best 3D maps of the LRP2 protein ever created," said Dr.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Michigan State University shooting: suspect is 43-year-old Black male with no ties to universityThe shooting Monday at Michigan State University left five people in a hospital in critical condition, according to officials. Three people also died in the shooting.
Read more »
Prairie View A&M University president Dr. Ruth Simmons joining Rice UniversityStarting her new role on April 1, Ruth Simmons will work with a variety of programs across campus and advise the president's office on various matters, according to Rice.
Read more »
Butler University student reflects on friend lost in the Michigan State University tragedyThe Michigan State mass shooting hits close to home for one Butler University student. Anna Dietz is a sophomore at Butler University, but her hometown is in Michigan.
Read more »
Researchers digitally reconstructed the two oldest spinosaurus brains'The skulls of all spinosaurus are so specialized for fish-catching, it’s surprising to see such ‘non-specialized’ brains.'
Read more »
One presumed dead in Columbia fireAt least one person escaped the house and received medical treatment, according to reliable but unofficial reports.
Read more »