Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species.
The monkey, which lived for 10 days before being euthanized, was made by combining stem cells from a cynomolgus monkey — also known as a crab-eating or long-tailed macaque, a primate used in bio medical research — with a genetically distinct embryo from the same monkey species. It’s the world’s first live birth of a primate chimera created with stem cells , the researchers said.
The researchers made the cells pluripotent — giving them the ability to organize into all the different cell types needed to create a live animal. Then they selected a subset of cells to inject into genetically distinct 4- to 5-day-old embryos from the same monkey species. The cells were also infused with a green fluorescent protein so the researchers would be able to determine which tissues had grown out of the stem cells.
China Monkey Chimera DNA Medical Research Endangered Species Stem Cells Primate
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