Scientists believe disorienting the malaria parasite may prevent it from causing harm UNIGEnews ScienceAdvances
At the end of each multiplication cycle, the newly-formed parasites leave their host red blood cells, destroying them and infecting new ones. It is this destruction of red blood cells that causes the waves of fever associated with malaria. Severe forms of malaria are linked to the obstruction of blood vessels by infected red blood cells.a human whose blood is infected with Plasmodium, the parasite changes its development program to colonize the intestine of its new host.
Surprisingly, this sensor is also present at other stages of the parasite lifecycle, notably when the parasite has to leave the red blood cell."We then observe exactly the same mechanism: without this sensor, Plasmodium is trapped in the red blood cells, unable to continue its infection cycle." However, scientists have not identified the human molecules detected by the parasite; identifying them could provide a better understanding of how waves of fever are caused by Plasmodium.
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