A simple switch of seasoning offers a cost-effective therapeutic option for survivors of stroke, according to a new analysis from the randomized Salt Substitute and Stroke Study.
The open-label, cluster-randomized clinical trial was conducted in 600 northern villages in China. The subgroup analysis consisted of patients who self-reported a hospital diagnosis of stroke.
In the sensitivity analyses, participants with repeated recurrent strokes during the follow-up period were excluded, imbalances in baseline characteristics were adjusted, and"possible" and"probable” and “definite" were added to the definition of primary outcome events. Concerns about hyperkalemia in the trial have been raised often, Daniel W. Jones, MD, from the Department of Medicine at the University of Mississippi Medical Center, Jackson, and colleagues point out in. They note that this subgroup analysis used common manifestations to evaluate the presence of hyperkalemia, including hospitalization and death related to arrythmia; neither increased in the salt-substitute group.
"Previous studies have clearly demonstrated that sodium reduction and potassium supplementation not only reduce independently but also have synergistic effects," note the study authors, led by Xiong Ding, MPH, with the School of Public Health at Wuhan University, China.
Cerebrovascular Accident CVA Cerebrovascular Accident (CVA) Stroke Risk Hypertension Blood Clinical Research Clinical Trials Clinical Studies Pre-Clinical Trial Double-Blind Study Double-Blind Studies Single-Blind Study Single-Blind Studies Recurrent Stroke Renal Disease Kidney Disease Kidney Disorder Renal Disorder Nephropathy Hyperkalemia Hyperkalaemia
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