Life science researchers use stem cells to create organoids, which represent human organs and allow greater knowledge of how the body behaves and reacts to disease.
Scientists at the Salk Institute have created a better brain. It’s a human brain, but it’s very small and it’s used for research. KPBS Sci-tech reporter Thomas Fudge tells us about organoids, and how they’ve changed life science research.
“We can grow them and expand a lot of organoids for a lot of screening and studies in vitro,” Wang said. “So we can identify a molecular pathway and then we can go back to the in vivo animal models to test this, so we can already have a theory before we go into animals to do these studies.”Meiyan Wang is a neuroscientist and a postdoctoral fellow at the Salk Institute stands in the Institute's cell culture lab. March 4, 2024.
“This sort of epitomizes what people are calling ‘personalized medicine.’ Because we have your cells here, and they can be tested with treatments and understand the mechanism,” Gage said. “But it's of your cells, not of a model system or an animal system.”
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