New technology uses light-activated dye to trigger immune response against deep-seated tumors, potentially revolutionizing cancer treatment.
For some cancers, light offers a powerful, minimally-invasive treatment. However, this light-activated drug therapy works wonders on surface cancers, but deeper ones are out of reach.
Until now, light therapy has been ineffective as these tumors burrow deep within the body, surrounded by a complex network of tissue, blood, and bone that protects cancerous cells from the curative power of light.The engineers and scientists have developed this new wireless, LED-device that works directly on the tumor.
“Certain colors of light penetrate tissue deeper than other ones,” said Thomas O’Sullivan, associate professor of electrical engineering and co-author of the paper. This burst of energy within the cancer cells does the trick: it turns their own oxygen toxic, leading them to self-destruct. This cell death phenomenon is known as pyroptosis.
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