A recent study published in Nature Communications demonstrates the use of cellulose nanofiber sheets to analyze the geographical heterogeneity of extracellular vesicles (EVs) through spatial exosome analysis. EVs play a crucial role in intercellular communication, and understanding their subpopulations is important for various physiological processes.
In a recent study published in the journal Nature Communications, researchers use cellulose nanofiber (CNF) sheets to show extracellular vesicle (EV) geographical heterogeneity by spatial exosome analysis . All live cells release EVs, which are crucial in intercellular communication. The biological properties of EVs may reflect their function, origin, and biogenesis, thus resulting in a wide range of EVs produced in physiological fluids .
Understanding EV subpopulations is critical; however, true heterogeneity is unattainable due to EVs continually moving in physiological fluids. For example, abdominal cavity tumors, such as those present in gastrointestinal and gynecological cancers, may lead to the accumulation of malignant ascites in these individuals
Cellulose Nanofiber Extracellular Vesicles Evs Spatial Exosome Analysis Intercellular Communication Physiological Fluids
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