Researchers solve an 80-year-old medical mystery that caused baby deaths uniofeastanglia
It led to a wave of baby deaths in the 1930s and 1940s, after foods such as milk, bread, cereal, and margarine were fortified with Vitamin D in a bid to eradicate rickets in children.
Dr. Green said,"Foods such as dairy products had been fortified with vitamin D, but it led to a number of baby deaths, and was eventually banned in many countries except for in breakfast cereals and margarine. The UEA team collaborated with colleagues at the Norfolk and Norwich University Hospital, where they worked with 47 patients.
"On a wider scale relevant to genetics and health, we know that genes must have the correct sequence to produce the correct protein, but in an added layer of complexity, we now know that genes also have to have a correct physical shape," added Dr. Green. "A beneficial side effect to some anti-fungal medications includes alteration of vitamin D metabolism lowering active vitamin D, which decreases calcium levels and can give patients a more normal quality of life, which we have started to prescribe in some patients," he added.This research was led by UEA in collaboration with the John Innes Centre, the Norfolk and Norwich University Hospital, Croydon University Hospital, and the Royal Hospital for Children in Glasgow.
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