Not only in the tropics do snake bites lead to dangerous envenoming—bites from European venomous snakes can also cause severe physical damage. But their venom also contains active substances that could be used against bacterial pathogens in the future.
IME in Giessen and the Hessian LOEWE Center for Translational Biodiversity Genomics are investigating the venoms of European snakes and have recently decoded the venom cocktail of the Milos viper native to Greece. Their study was published in the journalCobras, mambas, or rattlesnakes—most people are certainly aware that such venomous snakes can pose a danger to life and limb. Worldwide, almost 3 million snakebites occur every year, causing about 100,000 deaths, especially in tropical regions.
Hessian scientists from the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Justus Liebig University Giessen are therefore working on research projects within the framework of the LOEWE Center for Translational Biodiversity Genomics on the neglected venoms of adders. The scientists have now succeeded for the first time in decoding the venom composition of the notorious Milos viper .
"By applying state-of-the-art mass spectrometry, so-called proteomics, we were able to identify the components in the venom of the Milos viper for the first time. We can show that its venom cocktail is almost identical to the venoms of the various subspecies of the Levantine viper and must conclude that it has comparable potency," says Lüddecke.
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