Professor Bernd Rehm and Dr. Shuxiong Chen from the Griffith Institute for Drug Discovery (GRIDD) and Griffith's Center for Cell Factories and Biopolymers have succeeded in developing a new vaccine modality that is a stable particulate vaccine.
. The paper"Polymeric epitope-based vaccine induces protective immunity against group A Streptococcus" has been published inTo demonstrate this vaccine approach, it was tested with a more established Griffith vaccine against Strep A that is currently performing strongly inProfessor Rehm said the tests we've run so far show this technology facilitates development of vaccines that are safe and induce strong immune responses against Strep A.
"We developed a cost-effective manufacturing process and the resulting vaccines are ambient-temperature stable, strongly facilitating stockpiling and dissemination in developing countries where refrigeration is not always available." Globally, Strep A causes 700 million human infections each year and there are more than 500,000 deaths.
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