Early stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cells and degeneration of these cells. For most diseases, this selective vulnerability pattern is unexplained, yet it could yield major insight into pathological mechanisms.
Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease." ScienceDaily. ScienceDaily, 11 March 2024. <www.sciencedaily.com
The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of ... Many neurodegenerative diseases, such as dementia, are characterized by the abnormal aggregation of proteins inside cells, and treatments are being developed to break them up. But new research ...
Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy. It is characterized by the accumulation of neurotoxic proteins in the brain, ... Huntington's, Alzheimer's, ALS, and multiple other neurodegenerative diseases share a commonality: they are all characterized by proteins aggregating in neurons ...
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