Researchers have demonstrated a promising sterilization technique that uses X-ray irradiation to reduce Aspergillus flavus viability in contaminated corn. This method achieves sterilization without degrading the harmful aflatoxin B1 (AFB1) produced by the fungus.
Researchers have demonstrated a promising sterilization technique that uses X-ray irradiation to reduce Aspergillus flavus viability in contaminated corn. This method achieves sterilization without degrading the harmful aflatoxin B1 produced by the fungus.
By disabling Aspergillus flavus, the method stops the fungus from transmitting spores and producing more aflatoxins. This is crucial to allowing more laboratories to join the fight against fungal toxin prevention and control. Stabilizing toxin levels allows scientists to develop and test additional remediation techniques that target aflatoxin degradation without the complication of ongoing fungal growth.
Glesener is a graduate research assistant in the Biodesign Center for Health Through Microbiomes and a biological design PhD student in ASU's School for Engineering of Matter, Transport and Energy. Aflatoxin contamination is a significant global concern, especially in humid, tropical and subtropical regions. It is most prevalent in Africa, Asia and parts of South America, where warm conditions can jump-start the growth of Aspergillus species.
The World Health Organization estimates that aflatoxins contribute to approximately 5% to 28% of global cases of liver cancer, with the highest burden in sub-Saharan Africa, Southeast Asia and China. Every year, aflatoxin exposure is estimated to cause 25,000 to 155,000 liver cancer deaths worldwide. Further, the effects of aflatoxin exposure, even at lower levels, are more severe in animals.
Hannah Glesener, Darya Abdollahzadeh, Christopher Muse, Rosa Krajmalnik-Brown, Mark A. Weaver, Lee E. Voth-Gaeddert.The past attempts of honey bee researchers to inventory the fungal diversity in honey bee colonies revealed that Aspergillus flavus is frequently found in hives. In a new study, researchers have ...
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