Researchers discover new insights into the neurobiological origins of ataxia

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Researchers discover new insights into the neurobiological origins of ataxia
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A study investigated the origin of ataxia in the brain of patients with stroke. A significant number of the stroke lesions in the patients were located outside the cerebellum.

A new study by the University of Turku and Turku University Hospital in Finland investigated the origin of ataxia in the brain of patients with stroke. A significant number of the stroke lesions in the patients were located outside the cerebellum.

"Ataxia is primarily considered to originate from damage to the cerebellum or to structures directly connecting the cerebellum to the rest of the central nervous system. However, ataxia has been observed to occur even without damage to these structures, which has left its neurobiological mechanisms partly unclear," says Juho Joutsa, Professor of Neurology and the Principal Investigator of the research group at the University of Turku, Finland.

Finally, the researchers tested the predictive value of the identified brain network in a separate dataset of 96 stroke patients and showed that the strokes that occurred in the network did indeed predict the development of limb ataxia in these patients.

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