Shanghai Jiao Tong University (SJTU) researchers have developed a highly sensitive and reusable surface-enhanced Raman spectroscopy (SERS) microfluidics system that has achieved a detection limit lower than 10 ppt (parts per trillion) of harmful substances.
Researchers develop nanoparticle array implantation for sensitive and reusable detectionBy the polarization-modulated femtosecond laser-induced printing technique, the 100-nm-diameter gold particles are implant into the microchannels forShanghai Jiao Tong University researchers have developed a highly sensitive and reusable surface-enhanced Raman spectroscopy microfluidics system that has achieved a detection limit lower than 10 ppt of harmful substances.
"In most research, the SERS-active substrate is fabricated separately in advance and then integrated with, suffering from low fabrication efficiency and expensive costs. We need to find a fast and affordable technique. Here we are saying, why not implant nanoparticles into the microchannel directly?"
mol/L using laser-induced photoreduction. However, laser-reduced nanoparticles are susceptible to oxidization when exposed to air, which will affect their service lifetime. Moreover, the laser-fabricated structures are challenging to control in a uniform manner, limiting the improvement of sensitivity and reproducibility.
Thanks to the high stability and sensitivity, the researchers used this method to fabricate a SERS microfluidic system and monitor the online oxidation reaction, which helps them infer the reaction path.
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