Researchers presented a wearable bioelectronic system to deliver therapeutic agents associated with wound healing.
By Pooja Toshniwal PahariaSep 12 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in Scientific Reports, researchers presented a wearable bioelectronic system to deliver therapeutic agents associated with wound healing.
The system consisted of a three-dimensional printed custom polydimethylsiloxane delivery device integrated with a printed circuit board . Both the PCB and the PDMS had corresponding through-holes with metal connection pins covered in silver epoxy, permitting physical and electric integration. The modularly built system included solution-containing reservoirs, implanted electrodes, and capillary tubes filled with hydrogels.
Each PCB included four actuation pathways wherein current could be measured by connecting resistors in parallel with voltages supplied via the MCU or an externally located controller. The wired system relied on connecting the PCB to an external voltage controller and included computer-aided design assemblies of the PDMS and PCB subsystems.
Related StoriesParticularly, the gadget may supply charged biomolecules, ions, and electric fields continuously in the in vivo as well as ex vivo settings. This stand-alone technology might be expanded to function as a component of the closed-loop-type wearable medicine delivery platform. Due to the modularity of the integration process, the PDMS device structure remained unaltered while the PCB was upgraded to achieve varied degrees of system capability.
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