According to a study, the RNA (a type of genetic material) and other substances within urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier when they are more easily treated without invasive procedures.
According to a study, the RNA and other substances within urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier when they are more easily treated without invasive procedures.
According to a new study from scientists at The University of Texas at Arlington, Chan-Zuckerberg Biohub, and Stanford University, studying the RNA and other substances within urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier when they are more easily treated without invasive procedures.
In the study, the team collected urine samples from two groups of people -- healthy individuals and people with kidney stones. Researchers took two types of RNA from the urine -- cell-free RNA that floats freely in urine, and sediment RNA, which comes from solid particles. The types of RNA were then sequenced and analyzed, comparing the specimens from the healthy individuals to the ones with kidney stones.
The next phase of the research, Buonomo said, is working on advanced machine learning techniques to further fine-tune the types of differences that can be detected when comparing the RNA and protein signatures of healthy individuals to individuals with diagnosed diseases. They hope identifying additional biomarkers will pave the way for simpler, less invasive diagnostic procedures in the future.
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