Research helps to identify immunosuppressed people least likely to have COVID-19 antibodies

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Research helps to identify immunosuppressed people least likely to have COVID-19 antibodies
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New research involving the University of Southampton has identified which people with compromised immune systems are less likely to have COVID-19 antibodies—making them more vulnerable to a severe infection.

who are at increased risk are encouraged to attend if they are invited for a booster vaccine, in order to get the best protection against COVID-19."

People with suppressed immune systems could choose to enroll in the study if they had received at least three COVID-19 vaccine doses. More than 23 thousand people took part by doing a home finger-prick antibody test and reporting the results using an online portal., information about their condition, and their COVID-19 history, including number of vaccinations., and 86% with rare autoimmune disease.

," says co-author of the study Professor Sean Lim from the University of Southampton."In the future, we could offer home antibody tests to those who we know are least likely to have antibodies and provide them to have quick access to preventative treatments if this is the case. The findings could also help to develop bespoke booster vaccination schedules for different groups."

Dr. Peter Lanyon, Consultant Rheumatologist, Nottingham University Hospitals NHS Trust and Rare Diseases Clinical Lead, National Disease Registration Service, NHS England said,"This study demonstrates the utility of national rare disease registration to identify and invite whole population-based cohorts of people to participate in research that answers important clinical questions and can inform clinical practice and health policy.

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