Nature research paper: Remote neuronal activity drives glioma progression through SEMA4F
. Kaplan-Meier survival curve of individual gain-of-function and loss-of-function validation studies for EphA6 and EphA7. EphA6-GOF , EphA6-LOF , EphA7-GOF , EphA7-LOF .. Quantification of infiltration from these tumors across the P30-P70 timecourse. Infiltration was quantified based on the presence of tumor cells in contralateral cortex and analyzed via two-way analysis of variance .
Representative images of IUE-HGG GOF/LOF/CTL of EphA6 in P50 mice. Frozen sections were stained with Hoechst and native GFP was assessed for infiltration status into the contralateral cortex.. Representative images of IUE-HGG GOF/LOF/CTL of Epha7 in P50 mice. Samples assessed as outlined above .. Representative H&E staining of IUE-HGG tumors containing GOF and LOF of EphA6, EphA7, and Sema 4F.
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