Remdesivir alone is not enough, researchers conclude in first major COVID-19 trial of the drug

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Remdesivir alone is not enough, researchers conclude in first major COVID-19 trial of the drug
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The data, published in the New England Journal of Medicine, show the drug shortened the course of illness from an average of 15 days to about 11 days

.

"However, given high mortality despite the use of remdesivir, it is clear that treatment with an antiviral drug alone is not likely to be sufficient," they added."Future strategies should evaluate antiviral agents in combination with other therapeutic approaches or combinations of antiviral agents to continue to improve patient outcomes in Covid-19."

"Even though the trial was ongoing, the data and safety monitoring board made the recommendation to unblind the results to the trial team members from the NIAID, who subsequently decided to make the results public," the researchers wrote. But some critics complained that the data were not published and worried the federal government was rushing the results.

"Serious adverse events occurred in 114 patients in the remdesivir group and 141 patients in the placebo group," the researchers wrote.

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