The benefits of changing drinking behavior among those with higher intakes were due mainly to significant reductions in angina and ischemic stroke.
Among those with high alcohol intakes, lowering alcohol consumption to mild to moderate levels is associated with a 23% reduction in the risk for major adverse cardiovascular events , a large cohort study suggests.
People who drank heavily at baseline were categorized into two groups according to changes in alcohol consumption after their second health examination: Sustained heavy drinking or reduced drinking. The primary outcome was the occurrence of MACEs — ie, a composite of nonfatal myocardial infarction or angina undergoing revascularization, any stroke accompanied by hospitalization, and all-cause death.During a follow-up of 162,378 person-years, the group that continued heavy drinking experienced a significantly higher incidence of MACEs than the group that reduced drinking .
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