Christoph Diener discusses biomarkers for Alzheimer's, valproate exposure and congenital malformation, GLP-1s and vascular events, the MS–COVID vaccine link, and headache drugs.
Professor, Department of Neurology, Stroke Center- Headache Center, University Duisburg-Essen, Essen, Germany
Dear colleagues, I'm Christoph Diener, from the Faculty of Medicine at the University of Duisburg-Essen in Germany. Today, I would like to tell you about seven studies in neurology. in Sweden investigated how accurate plasma-based biomarkers are for the diagnosis of Alzheimer's disease. They recruited 600 patients with cognitive impairment, and they measured plasma phosphorylated tau 217, amyloid-beta 42, and amyloid-beta 40.
They analyzed 13 randomized studies with more than 65,000 patients with diabetes. Compared with placebo, the new antidiabetic drugs reduced major vascular events by 13%, all-cause mortality by 22%, the risk for stroke by 16%, and the risk for ischemic stroke by 25%.
Alzheimer Disease COVID-19 Vaccine Coronavirus Vaccine Migraine Migraine Headache Headache Biomarker Biological Marker Multi-Biomarker Disease Activity MBDA Multibiomarker Disease Activity Cognitive Impairment GLP-1 Receptor Agonists Glucagon-Like Peptide-1 Receptor Agonists Stroke Cerebrovascular Accident CVA - Cerebrovascular Accident Impairment Receptors
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