Around 2 percent of adults worldwide suffer from a condition called non-alcoholic steatohepatitis (Nash), an advanced form of non-alcoholic fatty liver disease.
To conduct our study, we recruited 16 participants with obesity, Nash and moderate to advanced liver scarring. Five of the participants were female and 11 were male. Most participants were white.
At the start of the study, participants were weighed, had their blood pressure taken, blood tests done and two scans that measured the health of their liver. These scans estimated how advanced their liver inflammation and scarring was and the amount of fat in their liver. Fourteen of the participants completed the 24-week study. Participants lost an average of 15 percent of their body weight, showing they largely adhered to the weight loss programme.
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