Proteomics reveals a distinct IFN-driven plasma cytokine response to COVID-19 in infants and young children ChildHealth Proteomics Coronavirus Disease COVID Immunity SARSCoV2 medrxivpreprint Stanford uni_tue CincyChildrens EmoryUniversity
By Dr. Priyom Bose, Ph.D.Feb 5 2023Reviewed by Benedette Cuffari, M.Sc. Although the severe acute respiratory syndrome coronavirus 2 , the causal agent of the coronavirus disease 2019 pandemic, predominantly infects adults, many children and infants can contract the mild or asymptomatic infection. Nevertheless, severe infection and mortality rates associated with COVID-19 are low among children.
Thus, the extent to which infants develop durable antibody responses, as well as T- and B-cell memory, to SARS-CoV-2 needs to be investigated. It is equally important to understand how COVID-19 impacts the maturing of infants' immune systems in the long term. Blood samples were also obtained from 48 adult COVID-19 patients and ten healthy adults, whose average age was around 59 years.
The experimental results of the current study also revealed that infants are vulnerable to new SARS-CoV-2 variants of concern. This finding was based on reduced serum neutralization titers in infants and young children infected with Omicron sublineages, such as BA.1, BA.2, BA.3, and BA.4/5, as well as the Delta variant.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Researchers at the University of Wolverhampton have received grant to develop male contraceptiveResearch leads at the University of Wolverhampton have been granted more than £120,000 by an American charity in a bid to develop a male contraceptive.
Read more »
New Covid variant, Orthrus, causing concern as it spreads rapidlyResearchers have called the strain's ability to beat vaccines 'extraordinary'
Read more »
COVID-19: People urged to book booster appointments before vaccine programme scaled downMore than 400,000 appointments are available at 2,800 sites across England until Sunday 12 February, the final day of the autumn booster campaign, after which the NHS will adopt a targeted approach focusing on vulnerable patients.
Read more »
Deadline for Covid booster jab approaches next week for under-50sThe deadline for a Covid booster jab approaches next week for under-50s 💉 Vaccine efforts will then become “more targeted' to protect people at higher risk of severe illness
Read more »
Will we ever know how many people died of covid-19 in China?Our own model predicted that if the virus spread unencumbered in China, between 1m and 1.5m people would die of covid during this wave
Read more »