More than 1 million Americans live with Crohn’s, a chronic and sometimes crippling bowel disease that affects the intestines and leads to digestive issues. But in 2024, breakthroughs could bring relief in different ways. Here's what to know.
a chronic and sometimes crippling inflammatory bowel disease that affects the intestines and leads to digestive issues. While some people may have mild symptoms or even be symptom-free at times, others get severe belly pain, diarrhea, fatigue, weight loss, anemia, and other life-threatening complications.
In 2024 alone, several developments have been announced that could bring relief in different ways. In California, for instance, researchers are developing a type of stem cell therapy that may help heal the intestinal lining and prompt a positive response from the immune system. The therapy has shown promising results in mouse models but still needs to be tested in human clinical trials.
As these types of studies continue, Dave cautioned IBD patients against going to unregulated stem cell clinics, which offer therapies that aren’t yet proven. The FDA hasn’t approved any treatments in this area, so stem cell offers are “still experimental” in the U.S., he said, and could lead to infections or other serious complications.When people with Crohn’s disease have flare-ups, they often report belly pain, diarrhea, and sometimes stool with blood or mucus.
“If there is a platform that could monitor the flare-up in real time, this would be significant so the treating physician can take appropriate and timely actions to help remedy the situation,” he said. “With the technological advance that we have described, this could one day become a reality so quality-of-life metrics for those afflicted can be greatly enhanced.”Across the U.S. and Canada, IBD specialists who focus on pediatric patients are working together to find better solutions for kids.
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