Profile of a killer: Unraveling the deadly new coronavirus

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Profile of a killer: Unraveling the deadly new coronavirus
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'We’re in a battle with something that we can’t see.' Here’s what we know about the coronavirus that has rescripted nearly every moment of daily life. RacingforaRemedy

“It just came back, that fear,” she said. “I just wanted to tell him not to give up.”

In short, the coronavirus has rescripted nearly every moment of daily life. And fighting it -- whether by searching for a vaccine or seeking to protect family -- takes knowing the enemy. It’s the essential first step in what could be an extended quest for some version of normalcy. But the coronavirus has a weakness: an outer membrane that can be destroyed by ordinary soap. That neutralizes the virus, which is why health experts emphasize the need to wash hands.

“People were getting increasingly excited and beginning to brainstorm ideas,” said Friedrich, who has spent years studying other infectious diseases. Scientists are fairly certain the disease originated in bats, which harbor many coronaviruses. To get to humans, it may have been passed through another animal, possibly consumed for meat. By late January, when Chinese authorities walled off the city of Wuhan, where the disease was first diagnosed, it was too late to stop the spread.

Soon after the first case in Wuhan, Chinese tourists with the virus traveled to France. But doctors there reported recently that a fishmonger contracted the disease even earlier than that, from an unknown source. On January 21, the first confirmed U.S. case was reported in Washington state, in a man who had traveled to Asia.

Even after five days in the hospital, Vivian Castro, the nurse who became infected, said she returned home struggling for air.The reason why becomes clear in autopsies of those who have died, some with lungs that weigh far more than usual. Under a microscope, evidence of the virus’ destruction is even more striking.

“Each autopsy has the chance to tell us something new,” she said. And those insights from the bodies of the dead could lead to more effective treatment of the living. “It’s difficult because they have so many problems and there are so many patients,” Moser said, “and you just want to do the right thing -- give people the best chance to get better.”In recent weeks, researchers have recruited 3,000 patients from around the world in a bid to solve a puzzling anomaly.

It’s not clear, for example, why the disease has had such a limited impact on children, compared to other age groups. People older than 65 are well over 100 times more likely to be hospitalized for the virus than people under 18. But so far, there’s no explanation why. Scientists wonder if children might have some key difference in their cells, such as fewer of the specialized proteins that the coronavirus latch onto. Or maybe their immune systems react differently than in adults.

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