Consuming more ultraprocessed food was linked to an increased risk for microvascular complications, especially diabetic kidney disease, in a cohort of patients with T2D.
, eating more ultraprocessed food increased the overall risk for microvascular complications and for diabetic kidney disease in particular. The risk was partly mediated by biomarkers related to body weight, lipid metabolism, and inflammation.A higher intake of UPF increases the risk for T2D and other metabolic morbidities; but whether this leads to an increased risk for diabetic microvascular complications remains largely unexplored.
Dietary information of participants was collected with a web-based 24-hour dietary recall tool that recorded the frequency of consumption of 206 foods and 32 beverages. Each 10% increase in the proportion of UPF consumption increased the risk for composite microvascular complications by 8% and diabetic kidney disease by 13% . No significant UPF intake association was found with diabetic retinopathy or diabetic neuropathy.
Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Renal Disease Kidney Disease Kidney Disorder Renal Disorder Nephropathy Kidneys Diabetic Retinopathy Retinopathy Retinal Disease Biomarker Biological Marker Multi-Biomarker Disease Activity MBDA Multibiomarker Disease Activity Neuropathy Diabetic Neuropathy Diabetic Neuropathies
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