Process analytical technology (PAT) for biopharmaceuticals
Sponsored Content by Wyatt TechnologyFeb 22 2023Reviewed by Olivia Frost A new white paper from Wyatt Technology explores real-time multi-angle light scattering as a process analytical technology for monitoring and controlling nanomedicines and biopharmaceuticals production processes. Additionally, it discusses the implementation of light-scattering-based on-line and in-line PAT.
While DLS and MALS are already important for both product development and process development via off-line detectors, they lack the ability to provide instantaneous feedback to process developers and manufacturing engineers. Wyatt's ultraDAWN MALS detector provides real-time capabilities for process monitoring: it quantifies product attributes such as molar mass, nanoparticle size and nanoparticle concentration up to 5 times per second.
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