Probiotics Emerge as Promising Intervention in Cirrhosis

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Probiotics Emerge as Promising Intervention in Cirrhosis
MicrobiotaComplementary And Alternative MedicineAlternative Treatment
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In patients with cirrhosis, probiotics reduce HE and improve liver function scores, quality of life, and gut flora, a systematic review and meta-analysis finds.

They also improve quality of life and have a favorable safety profile, adding to their potential as a promising intervention for treating cirrhosis, the study authors wrote.

Among 17 studies involving patients with different stages of HE, as compared with the control group, probiotics significantly reversed minimal HE and improved HE . In particular, the probiotic VSL#3 — which contains Streptococcus,In addition, probiotics appeared to improve liver function by reducing MELD scores but didn't show a difference in other liver function parameters.

"Overall, despite a number of methodological concerns, the study shows that probiotics can improve some disease markers in cirrhosis," Phillipp Hartmann, MD, assistant professor of pediatric gastroenterology, hepatology, and nutrition at the University of California, San Diego, told"One of the methodological concerns is that the authors compared probiotics with a multitude of different treatments, including fiber and lactulose , rifaximin , standard of care, placebo, or no...

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