A clinical trial into treatment for gestational diabetes, involving more than 500 pregnant women, has revealed what the lead academic has described as a significant step forward for women. The research has found benefits for both mothers and their newborn babies, and alleviated concerns over the use of the drug metformin, including less weight gain for mothers; no evidence of increase in preterm birth; and no differences in adverse neonatal outcomes.
Researchers at University of Galway have taken a significant step forward in the management of gestational diabetes mellitus after a clinical trial involving pregnant women provided new hope for expectant mothers suffering the condition.Gestational diabetes is a global health issue affecting almost 3 million pregnant women worldwide every year. It is a condition characterised by elevated blood sugar levels during pregnancy, posing increased health risks for both mothers and their babies.
Women receiving metformin gained less weight throughout the trial and maintained this weight difference at the 12-week post-delivery visit. While there was a slight reduction in infant length , there were no other significant differences in baby measurements. Additionally there were no variations in rates of labour induction, caesarean delivery, maternal haemorrhage, infection or blood pressure issues during or after birth."While there is convincing evidence that improved sugar control is associated with improved pregnancy outcomes, there was uncertainty about the optimal management approach following a diagnosis of gestational diabetes.
"For mothers with gestational diabetes, they are also at greater risk of high blood pressure and preeclampsia.
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