Emerging research explores how epigenetics and adults’ preconception experiences will affect their future children’s brains and behavior.
Preconception Experiences of Moms — and Dads — May Influence Babies’ Development, blue outline of stick figure family, with green DNA underneath themTo what extent can parents’ experiences before conception influence their offspring’s development, behavior, and long-term health? It’s an increasingly common question that scientists can’t answer — at least not yet.
So far, a handful of human studies have provided indirect support for preconception effects . However, it is difficult to establish whether preconception exposure or other related factors explain these effects. For example,exposure may affect parental mental health and increase risky behaviors, such as substance use, which may affect a child’s environment and development.
Moving the field forward will require large investments in studies that can collect epigenetic data in both parents and children and at different life stages , which is expensive and logistically challenging. However, the rise of longitudinal multi-generational studies, together with the decreasing costs of epigenetic profiling and rapid methodological advances to handle this large and complex data, will soon enable us to overcome these barriers.
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