Adding a PPI (omeprazole) to chemo may offer hope to women with triple-negative breast cancer, according to the results of a phase 2 trial.
plus a taxane), said lead author Sagar D. Sardesai, MBBS, a medical oncologist at Ohio State Comprehensive Cancer Center in Columbus.
“It’s exciting,” said Sardesai. “Overall, triple-negative patients who achieve a pCR have a very good outcome.”triple negative breast cancerNatalie Berger, MD, medical oncologist, Icahn School of Medicine at Mount Sinai, New York City, said the study’s pCR rates were “much higher” than expected and “intriguing and hypothesis generating.
The researchers, who include high-profile breast cancer specialist Kathy Miller, MD, of Indiana University, are seeking a National Cancer Institute or Department of Defense grant to mount a 100-plus patient randomized trial.
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