Post-COVID Syndrome and Its Relationship to Other Disorders Characterized by Fatigue and Exercise Intolerance

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Post-COVID Syndrome and Its Relationship to Other Disorders Characterized by Fatigue and Exercise Intolerance
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The authors of a new review know more about post-infection syndromes than does anyone else in the world and provide a must-read for all pulmonologists.

Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit., also known as post-COVID syndrome or long COVID, is a nebulous condition associated with an array of symptoms. The. Physiologic derangements responsible for these symptoms have been identified at the population level but are often opaque to the individual patients and their physicians.describes the challenge that is long COVID.

The article excels at describing the physiologic abnormalities that drive exercise intolerance; however, it offers little for the practicing clinician to apply at the bedside. The tables, flowcharts, and discussion all belie a clinical reality that goes unmentioned. iCPET is required to differentiate hyperventilation from gas-exchange abnormalities. iCPET is required to tease out deconditioning vs mitochondrial dysfunction vs preload dependence.

CPET confirms the presence of deconditioning/myopathy, which is ubiquitous both in isolation or combined with another disorder, and quantifies its severity. Itthat can be missed . Last, it can be used to educate patients and counsel them on anAaron B. Holley, MD, is a professor of medicine at Uniformed Services University in Bethesda, Maryland, and a pulmonary/sleep and critical care medicine physician at MedStar Washington Hospital Center in Washington, DC.

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