Medscape spoke with Professor Zhenyue Chen of Shanghai Jiao Tong University of Medicine in China about her research into the lipids that increase ASCVD risk.
is the leading cause of death globally despite many advances in its diagnosis and management. Improving the understanding of the disease has been one of the main research interests of cardiologistAs both a clinical and basic science researcher, Chen has been at the forefront of some important discoveries concerning the pathologic mechanisms underlying.
I have had a major focus on this for years and try to do some things that may help set up some new strategy, like reducing temperature to protect cardiomyocytes by either adjusting surrounding temperature or turning on some related gene expression, or we use some small molecules to target a new pathway and try to cure the disease. Right now, we are working on this in animal models and we try to set up a system that's safe and effective; then we will go back to the clinical setting.
In regard to your research into lipid metabolism, you have done a lot looking at Lp. What is Lp and why is Lp important? We have some new drugs on the way that will specifically target Lp. Maybe in 1 or 2 years we will have these medicines for Lp to resolve the problem. For now, the strategy for elevated Lp is to improve lifestyle and control overall risk factors of ASCVD, including reducing LDL-C intensively, to dilute the
If we need to define the patient in terms of risk stratification , Lp beyond 50 mg/dL will be considered as an enhancer of risk for ASCVD. But the cutoff for elevated CV risk or defining an enhancer is not the cutoff for initiating treatment. We are waiting for some results coming from a . The baseline Lp level for inclusion of a secondary prevention population is about 70 mg/dL, and there is a subgroup setting of 90 mg/dL.
Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Lipids Lipid Management Clinical Guidelines Guidelines Atherosclerosis Atherosclerotic Disease Of The Carotid Artery Heart Failure Atherosclerotic Heart Disease Atherosclerotic Cardiovascular Disease Coronary Heart Disease Ischemic Heart Disease Coronary Artery Disease Hypertension
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Research shows queen conch populations in marine reserves replenish populations beyond the reserve in The BahamasA new study published in Conservation Science and Practice uncovers how breeding populations of queen conch (Aliger gigas) within a protected marine reserve, where fishing is prohibited, sustain populations beyond the borders of the reserve.
Read more »
Neuroscience Surprise: Different Types of Love Light Up Different Parts of the BrainScience, Space and Technology News 2024
Read more »
The pros and cons of spraying pesticides to keep disease-carrying mosquito populations downSpraying pesticides can have unintended impacts on important pollinator species.
Read more »
Prison Populations Impact Rural, Urban Power in Ohio’s Census and RedistrictingAnti-gerrymandering groups in Ohio and nationally are looking to correct what they say is a representational flaw in redistricting regarding prison populations.
Read more »
The collapse of bat populations led to more than a thousand infant deathsA new study shows that when communities experienced the near death of entire insect-eating bat populations, farmers increased their use of pesticides. This in turn increased the infant mortality rate.
Read more »
Abbott’s order on Texas hospitals will alienate vulnerable populationsTexas State Representative Suleman Lalani writes about Abbott’s new order to collect immigration information from patients. This will only lead to a rise of...
Read more »