Popular weight-loss drugs like Wegovy may raise risk of complications under anesthesia

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Popular weight-loss drugs like Wegovy may raise risk of complications under anesthesia
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Patients taking blockbuster drugs like Wegovy for weight loss may face potentially deadly complications if they need surgery or other procedures that require empty stomachs for anesthesia.

Patients who take blockbuster drugs like Wegovy or Ozempic for weight loss may face life-threatening complications if they need surgery or other procedures that require empty stomachs for anesthesia. This summer's guidance to halt the medication for up to a week may not go far enough, either.

Nearly 6 million prescriptions for the class of drugs that include Wegovy and Ozempic were written between January and May in the U.S. for people who don't have diabetes, according to Komodo Health, a health care technology company. The drugs induce weight loss by mimicking the actions of hormones, found primarily in the gut, that kick in after people eat.

"When 90% of it is gone, which is after three weeks, hopefully everything should go back to normal," Jones said. Among the several reports detailing potentially serious problems was one of Hobai's patients, a 42-year-old man in Boston who recently began taking Wegovy, had to be intubated and suffered respiratory failure that put him in intensive care. He aspirated food that remained in his stomach despite fasting for 18 hours.

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