A research team has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.
A research team led by Professor Won Jong Kim from the Department of Chemistry at POSTECH, in collaboration with the Korea Disease Control and Prevention Agency , has developed a biodegradable polymer-based delivery system that efficiently transports mRNA. The study was recently published inSince the COVID-19 pandemic, global interest in mRNA vaccines has surged. Among existing delivery methods, lipid nanoparticles are widely used due to their high efficiency.
Furthermore, in immune response experiments, the polymer effectively induced T-cell activity and demonstrated comparable performance to LNPs in generating neutralizing antibodies against the COVID-19 virus. These findings highlight the potential of polymer-based delivery systems as a safer and more efficient alternative for next-generation mRNA vaccines and gene therapies.
This study was conducted as part of the new technology-based vaccine platform development project, co-implemented with the KDCA's National Institute of Health and funded by the National Research Foundation of Korea under the Ministry of Science and ICT.Hong Lyun Kim, Gurusamy Saravanakumar, Seowon Lee, Subin Jang, Seonwoo Kang, Mihyeon Park, Sivasangu Sobha, So-Hee Park, Soo-Min Kim, Jung-Ah Lee, Eunkyung Shin, You-jin Kim, Hye-Sook Jeong, Dokeun Kim, Won Jong Kim.
Gene Therapy Pregnancy And Childbirth Medical Topics Electronics Nanotechnology Materials Science Chemistry
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