Women with polycystic ovary syndrome showed an increased risk for cardiometabolic diseases, with the risk varying according to phenotype.
, metabolic dysfunction–associated steatotic liver disease , and cardiovascular disease , although these risks vary depending on PCOS phenotype.To understand the association between PCOS and the risk for cardiometabolic diseases, cancer, and dementia, researchers conducted a prospective study including 1008 women with PCOS and 5017 age- and body mass index–matched control participants without PCOS using data from the UK Biobank.
Liver, cardiac, and brain health were assessed using multiorgan MRI, and the impact of PCOS phenotypes on disease risk was evaluated.Incidence rates of T2D and all-cause CVD were higher in women with PCOS than in control participants.PCOS was significantly associated with the incidence of all-cause CVD in normoandrogenic PCOS but not in hyperandrogenic PCOS.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Polycystic Ovary Syndrome Polycystic Ovarian Disease Polycystic Ovarian Syndrome PCOS Stein-Leventhal Syndrome Metabolism Metabolic Ovaries Diabetes Mellitus Type 2 Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Liver Liver Disease Hepatic Impairment Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Dementia
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