Many people experience ongoing pain even after a urinary tract infection has supposedly passed. Now, research suggests this may be due to an overgrowth of nerve cells in their bladders
Pain that persists even after a urinary tract infection has supposedly passed seems to be down to an overgrowth of nerve cells in the bladder.making its way from faecal matter to the urethra, bladder or kidneys. Common symptoms include pain while urinating and the urge to urinate more often than normal. These infections mainly affect women,at Duke University in North Carolina. “But after treatment, some people seem to have the same UTI symptoms even when there’s no longer an infection.
The team found that those with persistent UTI symptoms had abnormal overgrowths of nerve cells in their bladders, compared with the other women. These nerve cells also had higher levels of a peptide called substance p, which causes pain and inflammation.had cleared. Taking a closer look at the mice’s bladders, the researchers found that immune cells called mast cells that were located near nerve cells were highly activated.
The team hopes the results could help with the development of an effective treatment to prevent ongoing symptoms in people. “We could actually prevent the growth of these nerves and thereby prevent the pain and frequency of urination,” says Abraham.
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