People Are Overdosing on Semaglutide Drugs like Ozempic and Wegovy

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People Are Overdosing on Semaglutide Drugs like Ozempic and Wegovy
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Dosing errors in the medication semaglutide, prescribed as Wegovy and Ozempic, can cause severe or prolonged gastrointestinal issues that require medical attention

As more people take the injectable weight-loss medication Wegovy, they should be aware of concerning reports of overdoses. That drug, more generally called semaglutide, can have unpleasant gastrointestinal side effects at prescribed doses. But if people take too much semaglutide, the adverse effects can be severe and even require hospitalization. The Food and Drug Administration

These conversions can be complicated. Doses are sometimes prescribed in milligrams but dispensed in syringes that are marked in milliliters—and these may be ambiguously referred to as “units.” Additionally, the syringes people receive can be far larger than the intended dose, potentially leading to a much higher one. According to the FDA, some individuals injected anywhere from five to 20 times the prescribed dose.

The injections are formulated to stay in a person’s system for up to a week but can persist even longer. This means that the symptoms from an overdose may need to be monitored and treated for an extended period of time.Doses vary depending on the individual. Doctors typically start patients on a low dose and adjust, or “titrate,” the amount upward every four weeks until they find a dosage that’s tolerable and maintains the desired weight-loss effects, Hwang says.

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